Crossregulation of the Thyroid Hormone and Corticosteroids in Amphibians and Fish: The Effects of Endocrine Disruption
نویسندگان
چکیده
Thyroid hormones are involved in many physiological processes, during growth, develop‐ ment, behaviour, stress. Their actions are mediated by TH receptors (TR-alpha and TR-beta), which are members of the nuclear receptor (NR) superfamily and function as ligand-activat‐ ed transcription factors. In amphibians, TR-alpha is expressed shortly after hatching and is maintained at a relatively constant level throughout tadpole life and metamorphosis. Then amphibian metamorphosis is dependent on thyroid hormone (TH) changes, which induces the suite of molecular and cellular changes that cause a tadpole to transform into a frog.
منابع مشابه
Smoking status and changes in thyroid-stimulating hormone and free thyroxine levels during a decade of follow-up: The Tehran thyroid study
Background: Smoking can cause thyroid disorders; the aim of the present study was to investigate the association between smoking status and changes in thyroid hormone levels among adult males during a decade long follow-up of in the Tehran Thyroid Study (TTS). Methods: Data of 895 adult males (smokers=115, non-smokers=691, ex-smokers=89) participants of the TTS without any previously known thy...
متن کاملEffects of endocrine disruption by 4-nonylphenol ethoxylate on the grwoth preformance and immune responses of female and male immature Koi carp (Cyprinus carpio carpio)
Nonylphenol (NP) is an endocrine disrupting chemical which has been shown to be able to modulate endocrine system of various organisms by different mechanisms. The objective of this study was to investigate the potential effects of 4-NP and 17-β-estradiol (E2) on immune parameters (IgM level and lysozyme activity) of Koi carp (Cyprinus the carpio carpio) in an attempt to expand the knowledg...
متن کاملEffect of human chorionic gonadotropin on sexual maturation, sex steroids and thyroid hormone levels in Caspian lamprey (Caspiomyzon wagneri Kessler, 1870).
The objective of this study was to determine the effect of human chorionic gonadotropin (hCG) on sexual maturation, plasma sex steroids (17β-estradiol, E2 and 17α-hydroxy progesterone (17α OHP)) and thyroid hormones (triiodothyronine, T3 and thyroxin, T4) levels in upstream - migrating Caspian lamprey. During the experiment, 36 fish (24 females and 12 males) in spring 2013 and 36 fish (24 fema...
متن کاملEffect of Aerobic Exercise on Thyroid Hormones and Quality of Life in Obese Postmenopausal Women
ABSTRACT Background and objectives: Studies have shown that exercise can affect hormone secretion and some metabolic and endocrine functions. The aim of this study was to assess the effect of eight weeks of aerobic training on thyroid hormones and quality of life in obese postmenopausal women. Methods: In this semi-experimental study, 21 obese (body mass index >30 Kg/m2)...
متن کاملThe role-playing autoantibodies in autoimmune thyroid diseases and their extra-thyroidal manifestations: review article
The presence of the antibodies against the main thyroid antigens, which include thyroid peroxidase (TPO) or microsomal antigen, thyroglobulin (Tg) as well as thyrotropin receptor or Thyroid Stimulating Hormone Receptor (TSH-R), is a hallmark and symbol of the autoimmune thyroid diseases (AITDs) as one of the most common autoimmune diseases (AD) around the world. The prevalence of the thyroid pe...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2013